| 发明名称 |
COMPOSITIONS AND METHODS FOR TREATING VASCULAR PERMEABILITY |
| 摘要 |
Retinal vascular permeability is reduced in the eye by administration of an inhibitor of Carbonic Anhydrase-1 (CA-1) and/or Carbonic Anhydrase-2 (CA-2) and optionally an inhibitor of Vascular Endothelial Growth Factor (VEG) signalling. Compounds and methods are provided for diagnosis and treatment of associated disorders in retina and brain. |
| 申请公布号 |
EP1858542(A4) |
申请公布日期 |
2009.08.19 |
| 申请号 |
EP20060735178 |
申请日期 |
2006.02.16 |
| 申请人 |
JOSLIN DIABETES CENTER, INC. |
发明人 |
FEENER, EDWARD, P.;AIELLO, LLOYD, P. |
| 分类号 |
A61K38/17;A61P9/10;C12Q1/25;C12Q1/527;C12Q1/68;G01N33/68 |
主分类号 |
A61K38/17 |
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