| 发明名称 |
DEPSIPEPTIDES AND THEIR THERAPEUTIC USE |
| 摘要 |
<p>Compounds which are Spiruchostatin analogues of the general formula (I) or (I′), isosteres thereof and pharmaceutically acceptable salts thereof are found to inhibit HDAC wherein R1, R2, R3 and R4 are the same or different and represent an amino acid side chain moiety and each R6 is the same or different and represents hydrogen or C1-C4 alkyl.</p> |
| 申请公布号 |
EP2089416(A1) |
申请公布日期 |
2009.08.19 |
| 申请号 |
EP20070848705 |
申请日期 |
2007.11.23 |
| 申请人 |
UNIVERSITY OF SOUTHAMPTON |
发明人 |
PACKHAM, GRAHAM KEITH;GANESAN, ARASU;CECIL, ALEXANDER RICHARD LIAM |
| 分类号 |
C07K5/02;A61K38/06;A61K38/15;A61P9/00;A61P25/00;A61P35/00;C07K11/00 |
主分类号 |
C07K5/02 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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