发明名称 |
ANTI-PROLIFERATIVE COMPOUNDS FROM A 3-ARYL-COUMARINE OR 3-ARYL-QUINOLIN-2-ONE AND USES THEREOF |
摘要 |
The present invention is directed to molecules deriving from a 3-aryl-coumarine or 3-aryl-quinolin-2-one and having potent anti-proliferative and/or cytotoxic activity, especially against tumoral cells. The present invention also concerns the uses of these molecules in therapeutic application, for the treatment of different cancers. The invention also discloses the use of said compound for the manufacture of a medicament for treating cancer. The invention also concerns a process for inhibiting cell proliferation comprising contacting said cells with a compound of the invention.
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申请公布号 |
US2009203685(A1) |
申请公布日期 |
2009.08.13 |
申请号 |
US20070301711 |
申请日期 |
2007.05.22 |
申请人 |
EOS (ETHICAL ONCOLOGY SCIENCE) S.P.A. |
发明人 |
SCHAPIRA MATTHIEU;LAMIGEON CYRILLE;GUTMANN MATHIEU;BARTHELAIX AUDREY;HUGO NICOLAS;COLAS PIERRE |
分类号 |
A61K31/5377;A61K31/366;A61K31/4704;A61K31/4709;C07D215/227;C07D311/06;C07D405/12;C07D407/12;C07D413/12 |
主分类号 |
A61K31/5377 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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