METHODS OF USING MIR-199A AS A MARKER AND SEQUENCES OF MIR-199A AS A THERAPEUTIC FOR CANCER

摘要

The invention relates to methods of measuring the level of expression of differentially expressed microRNAs (miRNAs), such as for example hsa-mir-199a, in a cancer cell as an indicator of the level of chemoresistance of the cancer cell. The invention further relates to methods of administering a nucleic acid, having a sequence based upon the sequence of a differentially expressed miRNA, such as for example hsa-mir-199a, to a cancer cell to diminish the chemoresistance of the cancer cell.