| 发明名称 |
IMIDAZOTHIAZOLE DERIVATIVES. |
| 摘要 |
<p>It is intended to provide novel compounds which inhibit the interaction between Mdm2 (murine double minute 2) protein and p53 protein and show an antitumor activity. Imidazothiazole derivatives having various substituents as represented by the following general formula (1), which inhibit the interaction between Mdm2 protein and p53 protein and show an antitumor activity, are provided, wherein R1, R2, R3, R4 and R5 in the general formula (1) are each as defined in the description.</p> |
| 申请公布号 |
MX2009006397(A) |
申请公布日期 |
2009.08.13 |
| 申请号 |
MX20090006397 |
申请日期 |
2007.12.12 |
| 申请人 |
DAIICHI SANKYO COMPANY, LIMITED |
发明人 |
NAITO, HIROYUKI;UOTO, KOUICHI;KAWATO, HARUKO;MIYAZAKI, MASAKI;SUGIMOTO, YUUICHI;OKAYAMA, TOORU;SOGA, TSUNEHIKO |
| 分类号 |
C07D513/04;A61K31/429;A61K31/4439;A61K31/454;A61K31/496;A61K31/4985;A61K31/5377;A61K31/551;A61P35/00;A61P43/00;C07D513/10;C07D519/00 |
主分类号 |
C07D513/04 |
| 代理机构 |
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