发明名称 GAMMA-GLUTAMYL TRANSPEPTIDASE INHIBITORS AND METHODS OF USE
摘要 <p>Enhancing the sensitivity of therapy-resistant tumor cells to antitumor agents such as chemotherapeutic agents and radiation by administering GGT inhibitor compounds that comprise a class of benzylthiadiazol benzenesulfomamides represented by the general structure Formula (1 ) The present invention also provides a method for the prophylaxis or treatment of a reversible airways obstruction in a mammal, such as a human, comprising administration of a therapeutically effective amount of a GGT inhibitor described herein for the prophylaxis or treatment of a disease associated with reverse airways obstruction such as asthma, chronic obstructive pulmonary disease (COPD), allergic reaction, respiratory tract infection or upper respiratory tract disease</p>
申请公布号 WO2009100121(A1) 申请公布日期 2009.08.13
申请号 WO2009US33063 申请日期 2009.02.04
申请人 THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA;HANIGAN, MARIE, H. 发明人 HANIGAN, MARIE, H.
分类号 A61K31/555;A61K31/675 主分类号 A61K31/555
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