DERIVATES OF SUBSTITUTED TARTARIC AICD AND USAGE FOR PREPARATING BETA SECRETASE INHIBITORS

摘要

Compounds represented by formula (I), or isomers, prodrugs, pharmaceutically acceptable salts, solvates or hydrates thereof in which each substituent of formula (I) as defined in the specification. The preparation methods of compounds represented by formula (I), pharmaceutically compositions, and the usage thereof for treating chronic neuro retrograde diseases such as Alzheimer's Disease and other diseases associated with aggregation or deposition of beta-amyloid polypeptide.