发明名称 METHODS FOR THE TREATMENT OF CARDIAC DISEASE ASSOCIATED TO MYOCARDIAL FIBROSIS USING AN INHIBITOR OF PCP
摘要 <p>The invention relates to methods for the treatment of cardiac diseases associated with fibrosis, in particular, chronic cardiac failure or hypertensive heart disease by the use of compounds which are capable of decreasing the activity of the Procollagen C-Proteinase or PCP. The invention also relates to methods for the developing a personalized therapy for the treatment of a patient suffering from a cardiac disease associated to myocardial fibrosis comprising determine in a sample from said patient a parameter indicative of the PCP activity and if the value of said parameter is higher than a predefined threshold value, then the patient is candidate to the treatment with a therapeutically effective amount of a PCP inhibitory agent, in particular, with torasemide.</p>
申请公布号 WO2009097893(A1) 申请公布日期 2009.08.13
申请号 WO2008EP51347 申请日期 2008.02.04
申请人 PROYECTO DE BIOMEDICINA CIMA, S.L.;LOPEZ SALAZAR, BEGONA;GONZALEZ MIQUEO, ARANTXA;DIEZ MARTINEZ, DOMINGO FRANCISCO JAVIER 发明人 LOPEZ SALAZAR, BEGONA;GONZALEZ MIQUEO, ARANTXA;DIEZ MARTINEZ, DOMINGO FRANCISCO JAVIER
分类号 A61K31/44;A61P9/04 主分类号 A61K31/44
代理机构 代理人
主权项
地址