发明名称 CRYSTALLINE BASE OF ESCITALOPRAM, AND ORODISPERSIBLE TABLETS COMPRISING ESCITALOPRAM BASE
摘要 PROBLEM TO BE SOLVED: To provide a method, by which escitalopram can efficiently be purified. SOLUTION: Provided is the method for reducing the content of escitalopram N-oxide in the free escitalopram base or its salt, characterized by dissolving the free escitalopram base in diethyl ether and removing the escitalopram N-oxide as a solid substance. COPYRIGHT: (C)2009,JPO&INPIT
申请公布号 JP2009179635(A) 申请公布日期 2009.08.13
申请号 JP20090115280 申请日期 2009.05.12
申请人 H LUNDBECK AS 发明人 DANCER ROBERT;PETERSEN HANS;NIELSEN OLE;ROCK MICHAEL HAROLD;ELIASEN HELLE;LILJEGREN KEN
分类号 C07D307/87;A61K31/343;A61P25/24;A61P43/00 主分类号 C07D307/87
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