发明名称 DIFLUORINATED TRIPEPTIDES AS HCV SERINE PROTEASE INHIBITORS
摘要 The present invention relates to compounds of Formula I, or a pharmaceutically acceptable salt, ester, or prodrug, thereof: which inhibit serine protease activity, particularly the activity of hepatitis c virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis c virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
申请公布号 US2009202486(A1) 申请公布日期 2009.08.13
申请号 US20090357854 申请日期 2009.01.22
申请人 GAI YONGHUA;OR YAT SUN;WANG ZHE 发明人 GAI YONGHUA;OR YAT SUN;WANG ZHE
分类号 A61K38/21;A61K38/06;A61P31/14;C07K5/08 主分类号 A61K38/21
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