摘要 |
In one embodiment the invention provides a genetically modified photoautotrophic, ethanol producing host cell comprising: - at least one first genetic modification changing the enzymatic activity or affinity of an endogenous host cell enzyme, - the first genetic modification resulting in an enhanced level of biosynthesis of acetaldehyde, pyruvate, acetyl - CoA or precursors thereof compared to the respective wild type host cell, - at least one second genetic modification different from the first genetic modification comprising an overexpressed enzyme for the formation of ethanol. |
申请人 |
BAIER, KERSTIN;DUEHRING, ULF;ENKE, HEIKE;GRUENDEL, MARIANNE;LOCKAU, WOLFGANG;SMITH, CRAIG, R.;WOODS, PAUL;ZIEGLER, KARL;OESTERHELT, CHRISTINE;COLEMAN, JOHN, ROBERT;KRAMER, DAN |
发明人 |
DUEHRING, ULF;ENKE, HEIKE;GRUENDEL, MARIANNE;LOCKAU, WOLFGANG;SMITH, CRAIG, R.;WOODS, PAUL;ZIEGLER, KARL;OESTERHELT, CHRISTINE;COLEMAN, JOHN, ROBERT;KRAMER, DAN |