HIGH PROTEIN CONCENTRATION FORMULATIONS CONTAINING MANNITOL

摘要

The present invention provides a method for inhibiting mannitol-induced aggregation of a protein in a liquid formulation by increasing the protein concentration to an amount greater than 50 mg/ml. The present invention also provides methods for storing and preparing a liquid formulation containing mannitol and a protein concentration greater than 50 mg/ml. ® KIPO & WIPO 2009