发明名称 |
Detection for HPV-Induced invasive cancers and their precursor lesions with invasive potential |
摘要 |
This invention provides a method of detecting an HPV-induced invasive cancer or precursor lesion thereof associated with tumor suppressor lung cancer 1 (TSLC1) in a subject in need thereof. The method comprises contacting a cell component of a test cell of the subject with a reagent that detects the level of the cell component in the test cell and determining a modification in the level of the cell component in the test cell as compared with a comparable healthy cell. The cell component indicates the level of TSLC1 in the cell, and a decrease in the level of TSLC1 indicates the presence of an HPV-induced invasive cancer or precursor lesion.
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申请公布号 |
US2009203072(A1) |
申请公布日期 |
2009.08.13 |
申请号 |
US20090378077 |
申请日期 |
2009.02.11 |
申请人 |
MEIJER CHRISTOPHORUS JOANNES L;STEENBERGEN RENSKE DANIELA MARIA;FERNIDANDUS SNIJDERS PETRUS JOSEPHUS |
发明人 |
MEIJER CHRISTOPHORUS JOANNES LAMBERTUS MARIA;STEENBERGEN RENSKE DANIELA MARIA;FERNIDANDUS SNIJDERS PETRUS JOSEPHUS |
分类号 |
A61K31/7052;A61K38/17;A61P35/00;C12Q1/02;C12Q1/68;C12Q1/70 |
主分类号 |
A61K31/7052 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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