| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a new catalyst for an azide-alkyne cycloaddition reaction, which can be recovered and recycled without being dissolved in a reaction solvent. <P>SOLUTION: The catalyst for the azide-alkyne cycloaddition reaction is obtained by fixing a copper catalyst dissolved in an ionic liquid onto a porous carrier. It is preferable that the copper catalyst is a copper bromide-dimethyl sulfide complex, the porous carrier is an amorphous silica gel having the thiol propyl group-modified surface and the ionic solvent is 1-butyl-3-methylimidazolium hexafluorophosphate. A triazole compound is produced by subjecting azide and alkyne to the cycloaddition reaction in the presence of this catalyst for the azide-alkyne cycloaddition reaction. <P>COPYRIGHT: (C)2009,JPO&INPIT |
