发明名称 |
DOWN REGULATION OF THE GENE EXPRESSION BY MEANS OF NUCLEIC ACID-LOADED VIRUS-LIKE PARTICLES |
摘要 |
The present invention relates to compositions of virus-like particles for the insertion of RNA-interference (RNAi) induced molecules into eukaryotic cells and a method for the cell type-specific transduction of a plurality of eukaryotic cells with RNAi-induced molecules. The present invention further relates to methods for the diagnosis, prevention, and/or treatment of diseases or disease states associated with an increased expression rate of at least one endogenic gene and/or with the undesired expression of at least one endogenic gene and/or foreign nucleic acids, particularly viral nucleic acids. |
申请公布号 |
WO2009036933(A3) |
申请公布日期 |
2009.08.13 |
申请号 |
WO2008EP07580 |
申请日期 |
2008.09.12 |
申请人 |
GRUBER, JENS;LUEKE, WOLFGANG |
发明人 |
GRUBER, JENS;LUEKE, WOLFGANG |
分类号 |
A61K31/713;A61K47/42;C12N7/04;C12N15/11;C12N15/113 |
主分类号 |
A61K31/713 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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