发明名称 |
NITRIC OXIDE DONOR COMPOUNDS |
摘要 |
The invention relates to nitric oxide donors of the formula (I) and pharmaceutically acceptable salts or stereoiso-mers thereof : wherein A and A' are independently selected from the group consisting of H and -(X)s-Y with the proviso that at least one of A or A' is not H; wherein s is 0 or 1; X is selected from the group consisting of : -CO-, -COO-, -CONH- and -SO2- or (A); Y is straight or branched C1-C20 alkyl chain, preferably C1- C10 alkyl chain, substituted with one or two -ONO2; or C1-C6 alkylenoxy- C1-C5 alkyl wherein the alkyl group is substituted by one or two -ONO2 groups. The invention also provides novel compositions comprising at least one compound of the invention and at least one therapeutic agent.
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申请公布号 |
CA2706082(A1) |
申请公布日期 |
2009.08.13 |
申请号 |
CA20092706082 |
申请日期 |
2009.01.15 |
申请人 |
NICOX S.A. |
发明人 |
ALMIRANTE, NICOLETTA;STEFANINI, SILVIA;STORONI, LAURA;NICOLI, FABIO;PADRON, JULIO LAZARO;BIONDI, STEFANO |
分类号 |
C07D493/04;A61K31/34;A61P9/00 |
主分类号 |
C07D493/04 |
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