发明名称 ADENOVIRUS FORMULATIONS
摘要 <p>The invention relates to viral formulations and related pharmaceutical products for use in gene therapy and/or vaccine applications. Especially preferred viral formulations disclosed herein are liquid adenovirus formulations, which show improved stability when stored in about the 2-8°C range while also being compatible with parenteral administration. These formulations comprise a buffer, a sugar, a salt, a divalent cation, a non-ionic detergent, as well as a free radical scavenger and/or a chelating agent to inhibit free radical oxidation.</p>
申请公布号 EP1263461(A4) 申请公布日期 2009.08.12
申请号 EP20010916434 申请日期 2001.03.06
申请人 MERCK & CO., INC. 发明人 EVANS, ROBERT, K.;VOLKIN, DAVID, B.
分类号 A61K9/08;A61K9/00;A61K35/76;A61K39/235;A61K47/00;A61K47/02;A61K47/10;A61K47/18;A61K47/26;A61K47/34;A61K47/46;A61K48/00;A61P31/12;A61P43/00;(IPC1-7):A61K39/12;A61K47/12;A01N63/00;A61P31/20 主分类号 A61K9/08
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