发明名称 |
MASS SPECTROMETRY OF BIOLOGICAL SAMPLE USING IMMUNOPRECIPITATION |
摘要 |
<p>It is intended to provide an analysis method for a biological sample with clinical significance, which is a system being simple to such an extent that it can be applied to a clinical field, and capable of capping a molecule ionization suppression in mass spectrometry. Mass spectrometry of a biological sample using immunoprecipitation, comprising the steps of: preparing a sample containing an objective biological molecule; concentrating the biological molecule in the sample by immunoprecipitation using an antibody-bound carrier or a carrier to which a molecule capable of specifically binding to an antibody is bound; washing an immunoprecipitate of the biological molecule by using an aqueous solution containing a charge neutralizing agent as a Mashing liquid; and detecting the biological molecule by subjecting the washed immunoprecipitate to mass spectrometry.</p> |
申请公布号 |
EP2088426(A1) |
申请公布日期 |
2009.08.12 |
申请号 |
EP20070829381 |
申请日期 |
2007.10.02 |
申请人 |
SHIMADZU CORPORATION |
发明人 |
SHIMADA, TAKASHI;TOYAMA, ATSUHIKO;SATO, TAKA-AKI |
分类号 |
G01N27/62;G01N33/48;G01N33/483 |
主分类号 |
G01N27/62 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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