发明名称 |
Composition containing chalcone |
摘要 |
The present invention provides an MMP-inhibitory composition comprising chalcone or its derivatives. They inhibit the MMPs in collagenase subfamily as well as those in gelatinase subfamily. The MMP inhibitory activity of chalcone derivatives was similar to or greater than that of parent compound, chalcone. Chalcone or its derivatives of the present invention inhibit activity of matrix metalloproteinase, so that it can be applied to treat and prevent diseases related to matrix metalloproteinase.
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申请公布号 |
US7572831(B2) |
申请公布日期 |
2009.08.11 |
申请号 |
US20040838853 |
申请日期 |
2004.05.03 |
申请人 |
ANGIOLAB, INC. |
发明人 |
KIM MIN-YOUNG;PARK BYUNG-YOUNG;KIM KYOUNG-MI;SUNG NACK-DO;MYUNG PYUNG-KEUN |
分类号 |
A61K31/235;A61K31/03;A61K31/12 |
主分类号 |
A61K31/235 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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