发明名称 |
A CONTRAST AGENT FOR DIAGNOSIS OF LIVER DISEASES AND PREPARATION METHOD THEREOF |
摘要 |
A contrast medium for diagnosing cancer diseases is provided to enable imaging from MRI (magnetic resonance imaging) to gamma imaging by injecting one contrast medium. A contrast medium of the chemical formula 1 for diagnosing cancer diseases using MRI (magnetic resonance imaging) comprises targets a superpra iron oxide nano particle, linker and ligand targeting parenchymal cell. In the chemical formula 1, SPIO is superpra iron oxide nano particle. The nano particle size is 4-200nm. The linker is dopamine. The ligand is lactobionic acid containing beta-glucose. A method for manufacturing the contrast medium comprises: a step of synthesizing and growing iron oxide nano particle; a step of reforming the iron oxide nano particle with linker; and a step of reforming the parenchymal cell with ligand.
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申请公布号 |
KR20090085835(A) |
申请公布日期 |
2009.08.10 |
申请号 |
KR20080011705 |
申请日期 |
2008.02.05 |
申请人 |
INDUSTRIAL COOPERATION FOUNDATION CHONBUK NATIONAL UNIVERSITY;CHONBUK NATIONAL VNIVERSITY HOSPITAL |
发明人 |
LEE, CHANG MOON;JEONG, HWAN JEONG |
分类号 |
A61K49/06 |
主分类号 |
A61K49/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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