发明名称 A CONTRAST AGENT FOR DIAGNOSIS OF LIVER DISEASES AND PREPARATION METHOD THEREOF
摘要 A contrast medium for diagnosing cancer diseases is provided to enable imaging from MRI (magnetic resonance imaging) to gamma imaging by injecting one contrast medium. A contrast medium of the chemical formula 1 for diagnosing cancer diseases using MRI (magnetic resonance imaging) comprises targets a superpra iron oxide nano particle, linker and ligand targeting parenchymal cell. In the chemical formula 1, SPIO is superpra iron oxide nano particle. The nano particle size is 4-200nm. The linker is dopamine. The ligand is lactobionic acid containing beta-glucose. A method for manufacturing the contrast medium comprises: a step of synthesizing and growing iron oxide nano particle; a step of reforming the iron oxide nano particle with linker; and a step of reforming the parenchymal cell with ligand.
申请公布号 KR20090085835(A) 申请公布日期 2009.08.10
申请号 KR20080011705 申请日期 2008.02.05
申请人 INDUSTRIAL COOPERATION FOUNDATION CHONBUK NATIONAL UNIVERSITY;CHONBUK NATIONAL VNIVERSITY HOSPITAL 发明人 LEE, CHANG MOON;JEONG, HWAN JEONG
分类号 A61K49/06 主分类号 A61K49/06
代理机构 代理人
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