PHARMACEUTICAL COMPOSITION BASED ON PEPTIDE REGULATING DISTURBANCES OF ANGIOGENESIS, AND WAY OF ITS APPLICATION

摘要

FIELD: medicine. ^ SUBSTANCE: invention relates medicine and concerns the pharmaceutical composition suitable for parenteral introduction, containing N-(-L-glutamyl)-L-lysine peptide of the general formula: H-Lys(H-Glu-OH)-OH, stimulating angiogenesis which can be used as a medical product for correction of angiogenesis disturbances. The invention provides intensifying of expression of a vascular endothelial growth factor gene, stimulation of metabolic activity, proliferation and migration of endotheliocytes, normalisation of cytokines production. ^ EFFECT: intensification of expression of a vascular endothelial growth factor gene, stimulation of metabolic activity, proliferation and migration of endotheliocytes, normalisation of cytokines production. ^ 5 cl, 7 ex, 3 dwg, 6 tbl