POLYVALENT VACCINE AGAINST SALMONID ALPHAVIRUS INFECTIONS

摘要

The present invention relates to a composition comprising salmonid alphaviru s or an antigenic and/or immunogenic material derived thereof, combined with one or more components selected from the group consisting of: a live, attenuated or killed bacterium, a virus other than salmonid alphavirus, said virus preferably being attenuated or inactivated, a fungus, a parasite; and an antigenic and/ or immunogenic material derived from any of these components. The invention further relates to a dosage form and a vaccine comprising the said composition and the invention provides for use of the composition in medicin e. Also, the invention relates to a method of manufacturing a composition or a vaccine as described above, and to a method of improving a polyvalent vaccin e, comprising including in the polyvalent vaccine an attenuated or inactivated salmonid alphavirus.