| 摘要 |
An antifreeze glycoprotein comprising at least one C-linked saccharide according to the following general formula: (see formula I) wherein X is nitrogen, sulfur, carbon or (CR1R2)n S=O wherein n is 0, 1, 2 o r 3, Y is carbon, nitrogen, sulfur or oxygen, R1 is hydrogen, methyl, fluorine, a carbohydrate , or a hydroxy chain, R2 is hydrogen, methyl, fluorine, a carbohydrate or a hydroxy chain, R3 to R6 independently represent an alkyl chain, a hydroxy group, a dimethyl sulfoxy group, a carbohydrate or an ether, R7 is ornithine, lysine, an alkyl chain, a pyridyl group or a heterocycle; and R8 is hydrogen, fluorine a carbohydrate or a hydroxy or methoxy group. Such antifreeze glycoprotein analogues are useful recrystallization inhibito rs and may be used as a cryoprotectant for tissue preservation and transplantation, improving the texture of processed frozen food and frozen meats, frostbite protection, crop protectio n, and green alternatives for land vehicle antifreeze and aircraft de-icing.
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