METHODS AND COMPOSITIONS FOR PROTEIN LABELING USING LIPOIC ACID LIGASES
摘要
The invention provides compositions and methods of use thereof for labeling peptide and proteins in vitro or in vivo. The methods described herein employ lipoic acid ligase or mutants thereof, and lipoic acid analogs recognized by lipoic acid ligase and lipoic acid ligase mutants.
申请公布号
WO2009064366(A3)
申请公布日期
2009.08.06
申请号
WO2008US12568
申请日期
2008.11.07
申请人
MASSACHUSETTS INSTITUTE OF TECHNOLOGY;TING, ALICE, Y.;SUAREZ, MARTA, FERNANDEZ;BARUAH, HEMANTA;CHOI, YOON-AA