发明名称 PYRIDAZINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS
摘要 A method of treating an SCD-mediated disease or condition in a mammal, preferably a human, includes administering to a mammal a compound of formula (I): where x, y, W, V, R2, R3, R4, R5, R6, R6a, R7, R7a, R8, R8a, R9 and R9a are defined herein. The SCD-mediated disease or condition may be selected from the group consisting of Type II diabetes, impaired glucose tolerance, insulin resistance, obesity, fatty liver, non-alcoholic steatohepatitis, dyslipidemia, metabolic syndrome, acne, cardiovascular disease, hypertriglyceridemia, inflammation, cancer, and any combination of these
申请公布号 US2009197890(A1) 申请公布日期 2009.08.06
申请号 US20090390117 申请日期 2009.02.20
申请人 XENON PHARMACEUTICALS INC. 发明人 GSCHWEND HEINZ W.;KODUMURU VISHNUMURTHY;LIU SHIFENG;KAMBOJ RAJENDER
分类号 A61K31/501;A61K31/00;A61K31/551;A61P3/06;A61P3/10;C07D213/75;C07D213/76;C07D213/81;C07D237/20;C07D237/22 主分类号 A61K31/501
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