The problems to be solved by this invention to provide a method of producing a medical instrument whereby a highly hydrophilic and lubricant coating layer having a high durability can be formed by a simple technique and thus highly hydrophilic and lubricant properties can be imparted to the surface of a medical instrument, and to provide an instrument for inserting an intraocular lens having been subjected to the surface treatment as described above. These problems can be solved by preparing a coating solution by mixing at least a water-insoluble polymer having carboxyl group and a polyfunctional reactive compound with an organic solvent, applying this solution on the surface of a medical instrument, conducting crosslinking and then performing a chemical reaction treatment whereby the coating layer is made hydrophilic. An instrument for inserting an intraocular lens is made hydrophilic by forming the coating layer as described above on the inner surface of an insertion tube, crosslinking and then performing the chemical reaction treatment.
