发明名称 BENZOXAZOLE CARBOXAMIDE INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP)
摘要 A compound having the structure set forth in Formula (I) or Formula (II): wherein the variables Y, R1, R2, R3, and R4 are as defined herein. Provided herein are inhibitors of poly(ADP-ribose)polymerase activity. Also described herein are pharmaceutical compositions that include at least one compound described herein and the use of a compound or pharmaceutical composition described herein to treat diseases, disorders and conditions that are ameliorated by the inhibition of PARP activity.
申请公布号 US2009197863(A1) 申请公布日期 2009.08.06
申请号 US20090355692 申请日期 2009.01.16
申请人 LEAD THERAPEUTICS, INC. 发明人 CHU DANIEL;WANG BING
分类号 A61K31/422;A61K31/423;A61K31/496;A61P35/00;C07D263/54;C07D413/02 主分类号 A61K31/422
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