发明名称 |
Novel Receptor Antagonists and Their Methods of Use |
摘要 |
The present invention relates to novel isoxazole derivatives of formula (I) which bind to the P2X7 receptor and are capable of interfering with the effects of ATP at the P2X7 receptor: and the use of such compounds or pharmaceutical compositions thereof in the treatment of disorders mediated by the P2X7 receptor, for example pain, inflammation and neurodegeneration.
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申请公布号 |
US2009197928(A1) |
申请公布日期 |
2009.08.06 |
申请号 |
US20070303262 |
申请日期 |
2007.06.05 |
申请人 |
GLAXO GROUP LIMITED |
发明人 |
BESWICK PAUL JOHN;WALTER DARYL SIMON |
分类号 |
A61K31/42;A61P25/28;C07D261/06 |
主分类号 |
A61K31/42 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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