发明名称 |
Lipidomic Approaches to Determining Drug Response Phenotypes in Cardiovascular Disease |
摘要 |
The present invention concerns the application of lipidomics to statin treatment for disorders such as cardiovascular disorders. Hence, the invention provides, among other things, a method of correlating a lipid profile with a positive or negative response to a statin treatment regimen by obtaining a lipid profile of a sample from a mammalian subject following commencement of the treatment regimen; and correlating the lipid profile in the sample with a positive or negative response to the treatment regimen. The invention further provides a method of correlating a lipid profile with a positive or negative response to a statin treatment regimen by obtaining a lipid profile of a sample from a mammalian subject before commencement of the treatment regimen; and correlating the lipid profile in the sample with a positive or negative response to the treatment regimen.
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申请公布号 |
US2009197242(A1) |
申请公布日期 |
2009.08.06 |
申请号 |
US20080257957 |
申请日期 |
2008.10.24 |
申请人 |
KADDURAH-DAOUK RIMA F;WIEST MICHELLE M;WATKINS STEVEN M;BAILLIE REBECCA A;PATNAIK MADHUMITA;KRISHNAN K RANGA RAMA;WEINSHILBOUM RICHARD M;KRAUSS RONALD M |
发明人 |
KADDURAH-DAOUK RIMA F.;WIEST MICHELLE M.;WATKINS STEVEN M.;BAILLIE REBECCA A.;PATNAIK MADHUMITA;KRISHNAN K. RANGA RAMA;WEINSHILBOUM RICHARD M.;KRAUSS RONALD M. |
分类号 |
C12Q1/00 |
主分类号 |
C12Q1/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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