发明名称 |
CHKL INHIBITORS WITH B CELL DEPLETING ANTIBODIES FOR THE TREATMENT OF HEMATOLOGIC MALIGNANCIES |
摘要 |
The present invention discloses, in part, therapies for treating hematologic malignancies, including B cell lymphomas and leukemias or B cell related tumors comprising the administration of a CHK1 inhibitor in combination with a B cell depleting antibody. The present invention further includes treating hematologic malignancies, including B cell lymphomas and leukemias, or B cell related tumors, which are resistant to cancer treatment comprising the administration of a CHK1 inhibitor. |
申请公布号 |
WO2008132500(A3) |
申请公布日期 |
2009.08.06 |
申请号 |
WO2008GB50288 |
申请日期 |
2008.04.24 |
申请人 |
ASTRAZENECA AB;ASTRAZENECA UK LIMITED;BROWN, JENNIFER;ZABLUDOFF, SONYA |
发明人 |
BROWN, JENNIFER;ZABLUDOFF, SONYA |
分类号 |
A61K39/395;A61K31/4535;A61K31/454;A61K31/4545;A61K31/7068;A61K31/7076;A61K45/06;A61P35/00;A61P35/02 |
主分类号 |
A61K39/395 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|