发明名称 |
ISOLATION OF OSTEOINDUCTIVE PROTEINS |
摘要 |
<p>A method for purifying bone-derived osteoinductive proteins including a demineralization process, a protein extraction process, a high molecular weight ultrafiltration process, a low molecular weight ultrafiltration process, and a recovery process. The high and low ultrafiltration processes preferably select proteins having a nominal molecular weight between approximately 8 kilodaltons and approximately 100 kilodaltons. Processes of the present invention may be used to recover osteoinductive proteins from bone demineralization waste streams.</p> |
申请公布号 |
EP2084177(A2) |
申请公布日期 |
2009.08.05 |
申请号 |
EP20070871149 |
申请日期 |
2007.10.11 |
申请人 |
ZIMMER ORTHOBIOLOGICS, INC. |
发明人 |
THORNE, KEVIN;AKELLA, RAMA |
分类号 |
C07K1/34;A61K38/18;C07K1/36;C07K14/51 |
主分类号 |
C07K1/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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