ENO1-SPECIFIC HUMAN ANTIBODY

摘要

A human antibody comprising a complementarity determining region (CDR) and framework region (FR) which are induced from a human is provided to use for cancer diagnosis, disease classification, imaging, treatment, and prognosis determination. A human antibody which is specific to ENO1 comprises: a heavy chain CDR (HCDR) 1 which is a polypeptide among sequence numbers 7-12; a polypeptide HCD 2 among the sequence numbers 13-18; a heavy chain having various heavy site (VH) comprising a HCD 3 which is polypeptide among sequence numbers 19-24 and its immunologically active fragment; a light chain CDR 1 which is a polypeptide among sequence numbers 31-36; and a polypeptide LCDR 2 among sequence numbers 37-42.