发明名称 Method for producing 4-nitroimidazole compound
摘要 The present invention provides a method for producing a 4-nitroimidazole compound represented by general formula (1) at high yield and at high purity by a safe method causing few dangers such as explosion. The production method of the present invention comprises iodinating a 4-nitroimidazole compound represented by general formula (2): wherein each of X1 and X2 represents a chlorine atom or bromine atom, and then reducing the obtained 5-iodo-4-nitroimidazole compound represented by general formula (3): wherein X2 is the same as defined above.
申请公布号 US7569702(B2) 申请公布日期 2009.08.04
申请号 US20050589864 申请日期 2005.02.15
申请人 OTSUKA PHARMACEUTICAL CO., LTD. 发明人 SHINHAMA KOICHI
分类号 C07D233/68;A61K31/4164;C07D233/91;C07D233/92 主分类号 C07D233/68
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