发明名称 |
Method for producing 4-nitroimidazole compound |
摘要 |
The present invention provides a method for producing a 4-nitroimidazole compound represented by general formula (1) at high yield and at high purity by a safe method causing few dangers such as explosion. The production method of the present invention comprises iodinating a 4-nitroimidazole compound represented by general formula (2): wherein each of X1 and X2 represents a chlorine atom or bromine atom, and then reducing the obtained 5-iodo-4-nitroimidazole compound represented by general formula (3): wherein X2 is the same as defined above.
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申请公布号 |
US7569702(B2) |
申请公布日期 |
2009.08.04 |
申请号 |
US20050589864 |
申请日期 |
2005.02.15 |
申请人 |
OTSUKA PHARMACEUTICAL CO., LTD. |
发明人 |
SHINHAMA KOICHI |
分类号 |
C07D233/68;A61K31/4164;C07D233/91;C07D233/92 |
主分类号 |
C07D233/68 |
代理机构 |
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地址 |
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