| 摘要 |
<p>Provided is a composition formulated for Injection Into a posterior segment of an eye of a human or animal comprising: (a) a corticosteroid component present in a therapeutically effective amount, wherein said corticosteroid component has a solubility in water at 25 degrees of Iess than 10 mg/mI, and wherein said corticosterold component is present in a plurality of particles; (b) a viscosity inducing component in an amount effective to increase the vlscosity of the composition; and; (e) an aqueous carrier component, wherein the corticosteroid particles are suspended in the composition and remain suspended in the composition for at least 1 week without requiring resuspension processing; ,wherein the viscosity inducing component Is selected from the group of conslsting of hyaluronic acid. metal hyaluronates, carbomer, polyacrylic acid, cellulosic derivatives, polycarbophil, gelatin, dextrin, polysaccharides, polyacrylamide, polyvinyl alcohol, polyvinyl acetate and mixtures thereof; and wherein the composition Includes no added preservative component.</p> |
