摘要 |
PROBLEM TO BE SOLVED: To provide pyrazole-benzimidazole derivatives useful for treating or preventing various diseases including cancer as inhibitors of KDR receptors. SOLUTION: Compounds is represented by formula (IAb) [wherein Ab is a substituted pyrazol-3-yl group, and the other substituents A<SB>1</SB>b, A<SB>2</SB>b, A<SB>3</SB>b, A<SB>4</SB>b, and A<SB>5</SB>b are as defined in the specification]. The compounds of the formula (IAb) may possibly be isomeric forms including racemates, enantioisomers or diastereoisomers and/or may be any possible adducts of the compounds of formula (IAb) with inorganic acids and organic acids or with inorganic bases and organic bases. COPYRIGHT: (C)2009,JPO&INPIT
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