| 摘要 |
PROBLEM TO BE SOLVED: To provide a sample adjusting method for mass analysis due to a matrix assisting laser elimination ionization method for forming the fine crystals of a matrix and a biomolecule such as biomolecule protein or the like on biotissue in order to form ions with high efficiency to enable measurement of high sensitivity. SOLUTION: A matrix solution is preliminarily sprayed on a protein sample to preform the fine crystal layer of the matrix. When the matrix solution is further dispensed on the fine crystal layer, crystals grow using preformed fine matrix crystals as nuclei. Accordingly, very fine homogenous eutectic crystals are formed and mass analysis due to MALDI can be performed with high sensitivity. COPYRIGHT: (C)2009,JPO&INPIT
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