| 发明名称 |
TREATMENT OF PORTAL HYPERTENSION AND RELATED CONDITIONS BY COMBINED INHIBITION OF THE VEGF AND PDGF SIGNALLING PATHWAYS |
| 摘要 |
<p>The present invention relates to the treatment and/or prevention of portal hypertension and manifestations related thereof, by the inhibition of both platelet-derived growth factorand vascular endothelial growth factor signalling pathways. Combinations of VEGF and PDGF signalling pathways inhibitors are disclosed for the treatment and/or prevention of portal hypertension, e.g. rapamycin and imatinib, sorafenib.</p> |
| 申请公布号 |
WO2009092442(A1) |
申请公布日期 |
2009.07.30 |
| 申请号 |
WO2008EP50770 |
申请日期 |
2008.01.23 |
| 申请人 |
UNIVERSIDAD DE BARCELONA;INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI ISUNYER (IDIBAPS);BOSCH GENOVER, JAIME;FERNANDEZ LOBATO, MERCEDES |
发明人 |
BOSCH GENOVER, JAIME;FERNANDEZ LOBATO, MERCEDES |
| 分类号 |
A61K31/00;A61K31/436;A61K31/4412;A61K31/506;A61K45/06;A61P1/16;A61P9/12 |
主分类号 |
A61K31/00 |
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