Disclosed herein are compositions and methods for deleting or duplicating DNA in a mammalian genome. Also disclosed are compositions and methods for generating a random genome-wide chromosome rearrangement. Also disclosed are compositions and methods for streamlined construction of gene targeting vectors.
申请公布号
WO2008098181(A8)
申请公布日期
2009.07.30
申请号
WO2008US53446
申请日期
2008.02.08
申请人
UNIVERSITY OF UTAH RESEARCH FOUNDATION;WU, SEN;CAPECCHI, MARIO, R.