| 发明名称 |
MATRIX FOR SUSTAINED, INVARIANT AND INDEPENDENT RELEASE OF ACTIVE COMPOUND |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a pharmaceutical composition for treating opioid-induced constipation as an opioid-induced adverse effect, idiopathic pruritus, pruritus caused by cholestasis and/or renal dysfunction or irritable bowel syndrome. <P>SOLUTION: The shelf-stable pharmaceutical composition contains about 1-50 mg naloxone in a non-swellable non-corrosive matrix, provided that the matrix contains ethyl cellulose and at least one fatty alcohol for retaining its sustained-release property. <P>COPYRIGHT: (C)2009,JPO&INPIT |
| 申请公布号 |
JP2009167198(A) |
申请公布日期 |
2009.07.30 |
| 申请号 |
JP20090061144 |
申请日期 |
2009.03.13 |
| 申请人 |
EURO-CELTIQUE SA |
发明人 |
BROEGMANN BIANCA;MUEHLAU SILKE;SPITZLEY CHRISTOF |
| 分类号 |
A61K9/24;A61K31/485;A61K9/00;A61K9/14;A61K9/16;A61K9/20;A61K9/22;A61K9/28;A61K9/48;A61K9/52;A61K9/72;A61K31/00;A61K47/02;A61K47/04;A61K47/10;A61K47/12;A61K47/26;A61K47/34;A61K47/36;A61K47/38;A61P1/04;A61P1/10;A61P13/12;A61P17/04;A61P25/04 |
主分类号 |
A61K9/24 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
