发明名称 |
METHODS FOR THE DIAGNOSIS AND TREATMENT OF CRITICALLY ILL PATIENTS WITH ENDOTHELIN, ENDOTHELIN AGONISTS AND ADRENOMEDULLIN ANTAGONISTS |
摘要 |
The ratio of concentrations of pro-adrenomedullin (pro-ADM)/pro-endothelin (pro-END) immunoreactivity in body fluids of critically ill patients is used as for the diagnosis, course control and prognosis, including an assessment of the mortality risk, of severe life threatening diseases. Further, a treatment of critically ill patients having high levels of pro-ADM but insufficient levels of pro-END immunoreactivities with a medicament comprising vasoconstrictive endothelin or its precursors, and/or endothelin agonists or adrenomedullin antagonists is provided.
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申请公布号 |
US2009191220(A1) |
申请公布日期 |
2009.07.30 |
申请号 |
US20090364911 |
申请日期 |
2009.02.03 |
申请人 |
BERGMANN ANDREAS;STRUCK JOACHIM;MORGENTHALER NILS G |
发明人 |
BERGMANN ANDREAS;STRUCK JOACHIM;MORGENTHALER NILS G. |
分类号 |
A61K39/395;C12Q1/02;G01N33/543;G01N33/68 |
主分类号 |
A61K39/395 |
代理机构 |
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地址 |
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