发明名称 |
IN VITRO DIFFERENTIATION/INDUCTION OF LYMPHOCYTE FROM STEM CELL HAVING GENOTYPE PROVIDED AFTER GENE RECONSTITUTION |
摘要 |
<p>The present invention provides a production method of a functional differentiated cell having a post-rearrangement genotype of a particular antigen receptor gene, which includes culturing a stem cell having the genotype in a medium to give the differentiated cell derived from the stem cell. As the stem cell having the genotype, a stem cell (e.g., ES cell) established by transplantation of the nucleus of a cell having the genotype is preferable. As the differentiated cell, NKT cell is preferable.</p> |
申请公布号 |
EP2083076(A1) |
申请公布日期 |
2009.07.29 |
申请号 |
EP20070828288 |
申请日期 |
2007.09.21 |
申请人 |
RIKEN |
发明人 |
WAKAO, HIROSHI;FUJII, SHIN-ICHIRO;SHIMIZU, KANAKO;KOSEKI, HARUHIKO;TANIGUCHI, MASARU;OGURA, ATSUO;KAWAMOTO, HIROSHI |
分类号 |
C12N15/09;A61K35/14;A61P35/00;A61P37/02;A61P43/00;C12N5/10;C12N15/00 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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