| 发明名称 |
Monoclonal antibody which agglutinates E. coli having the CS4-CFA/I family protein |
| 摘要 |
A monoclonal antibody to a consensus peptide of the formula: <tables id="TABLE-US-00001" num="00001"> <table frame="none" colsep="0" rowsep="0" tabstyle="monospace"> <tgroup align="left" colsep="0" rowsep="0" cols="2"> <colspec colname="1" colwidth="161pt" align="left"/> <colspec colname="2" colwidth="56pt" align="left"/> <tbody valign="top"> <row> <entry>VEKNITVTASVDPTIDLLQADGSALPSAVALTYSPA.</entry> <entry>(SEQ ID NO:1)</entry> </row> </tbody> </tgroup> </table> </tables> The monoclonal antibody of the invention binds exclusively to the sequence SAVALTYS (SEQ ID NO:2) and has use as a diagnostic and for prophylaxis against illness arising from E. coli which produce the CS4-CFA/I family of proteins and for treatment of disease arising therefrom.
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| 申请公布号 |
US7566540(B2) |
申请公布日期 |
2009.07.28 |
| 申请号 |
US20040864803 |
申请日期 |
2004.06.10 |
| 申请人 |
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY |
发明人 |
CASSELS FREDERICK J.;LEES ANDREW;SCHUMAN RICHARD F. |
| 分类号 |
G01N33/53;C07K14/245;C07K16/12;G01N33/569 |
主分类号 |
G01N33/53 |
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