METHOD FOR EXPERIMENTAL MODELING OF SYNDROME OF DIABETIC'S FOOT WITH SCARIFICATION-SORPTION METHOD

摘要

Method for modeling syndrome of “diabetic’s foot” through one-time intraperitoneal introduction to experimental animal (rat) of 5 % solution of aloxan in dose 170 mg/kg of body mass after 24-hour starvation. In 13 days in skin wound of animal under investigation by means of capshuc seam one fixes silica-gel container with mix of aerobic and anaerobic microorganisms (S.aureus, S.epіdermіdіs, B.fragіlіs, Peptococcus spp. and Fusobacterіum spp.).