发明名称 |
ISOLATED PEPTIDES AND USES THEREOF |
摘要 |
The present invention provides isolated preproinsulin-derived peptides of 8 or 9 amino acids, comprising the amino acid sequence WGPDPAA (SEQ ID NO: 1), isolated Class I peptide-HLA complexes presenting said peptides and isolated molecules having binding affinity for said peptides and/or said peptide-HLA complexes. Such compositions are useful in the treatment of Type 1 diabetes mellitus (TlDM) |
申请公布号 |
WO2009004315(A8) |
申请公布日期 |
2009.07.16 |
申请号 |
WO2008GB02223 |
申请日期 |
2008.06.27 |
申请人 |
KING'S COLLEGE LONDON;PEAKMAN, MARK;CALVINO, RUBEN VARELA |
发明人 |
PEAKMAN, MARK;CALVINO, RUBEN VARELA |
分类号 |
C07K14/62;A61K38/08;A61K38/28;C07K7/06;G01N33/68 |
主分类号 |
C07K14/62 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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