CREN7 CHIMERIC PROTEIN

摘要

There is provided a chimeric protein comprising a nucleic acid modifying enzyme domain having nucleic acid modifying activity joined with an Cren7 enhancer domain or variant thereof, in which the Cren7 enhancer domain or variant thereof enhances the activity of the nucleic acid modifying enzyme domain compared with a corresponding protein lacking the Cren7 enhancer domain or variant thereof. There is also provided an isolated nucleic acid encoding the chimeric protein of the invention and methods utilising the protein.