发明名称 |
Diagnosis of sepsis using mitochondrial nucleic acid assays |
摘要 |
The invention provides assays to detect sepsis disease states in a subject by determining the relative amount of mitochondrial nucleic acid in the subject. The assays of the invention may include PCR assays, such semi-quantitative or quantitative PCR involving the co-amplification of a mitochondrial sequence and a reference sequence, such as a genomic sequence. Information from such assays may be evaluated to provide a ratio of mitochondrial nucleic acid to nuclear nucleic add in the cells of the subject.
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申请公布号 |
US2009181367(A1) |
申请公布日期 |
2009.07.16 |
申请号 |
US20070900918 |
申请日期 |
2007.09.12 |
申请人 |
COTE HELENE;MONTANER JULIO;O'SHAUGHNESSY MICHAEL V |
发明人 |
COTE HELENE;MONTANER JULIO;O'SHAUGHNESSY MICHAEL V. |
分类号 |
C12N15/09;C12Q1/68 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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