LYOPHILIZED PHARMACEUTICAL COMPOSITION WITH IMPROVED RECONSTITUTION TIME CONTAINING TAXANE DERIVATIVES AND METHOD OF MANUFACTURING THE SAME

摘要

The present invention relates to a lyophilized composition with an improved reconstitution time comprising a taxoid and a method thereof. More specifically, the present invention relates to a lyophilized composition with an improved reconstitution time prepared by mixing and dissolving a taxoid; cyclodextrin(CD); a hydrophilic polymer selected from the group consisting of hydroxypropylmethyl CeIIuIoSe(HPMC), polyethylene glycol(PEG), and polyvinylpyrrolidone(PVP); and a bulking agent of saccharides in water for injection; and lyophilizing the mixture, and a method thereof.