| 发明名称 |
CONSTRUCTION OF WEST NILE VIRUS AND DENGUE VIRUS CHIMERA FOR USE IN LIVE VIRUS VACCINE TO PREVENT DISEASE CAUSED BY WEST NILE VIRUS |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide an attenuated chimera flavivirus having immunogenicity. <P>SOLUTION: Provided is a nucleic acid chimera containing a first nucleotide sequence encoding at least one structural protein of West Nile virus and a second nucleotide sequence encoding a nonstructural protein of the wild type of dengue virus. <P>COPYRIGHT: (C)2009,JPO&INPIT |
| 申请公布号 |
JP2009153520(A) |
申请公布日期 |
2009.07.16 |
| 申请号 |
JP20090058277 |
申请日期 |
2009.03.11 |
| 申请人 |
USA GOVERNMENT |
发明人 |
PLETNEV ALEXANDER G;PUTNAK JOSEPH R;CHANOCK ROBERT M;MURPHY BRIAN R;WHITEHEAD STEPHEN S;BLANEY JOSEPH E SR |
| 分类号 |
C12N15/09;A61K31/7088;A61K39/00;A61K39/12;A61K39/295;A61P31/12;A61P31/14;C07K14/18;C12N7/04;C12N15/86 |
主分类号 |
C12N15/09 |
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