METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCERS AND PATHOGENIC INFECTIONS
摘要
<p>The subject application provides small compounds that are able to suppress autophagy in various cells. These compounds are useful in augmenting the existing treatments of various cancers and microbial/parasitic infections. Thus, the subject application also provides methods of treating various types of cancers and microbial/parasitic infections. Also provided by the subject application are methods of suppressing the expansion of autophagosomes within cells or individuals and inhibiting the lipidation of autophagy-related protein 8 (Atg8).</p>
申请公布号
WO2009089147(A2)
申请公布日期
2009.07.16
申请号
WO2009US30102
申请日期
2009.01.05
申请人
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.;DUNN, WILLIAM, A.;AKIN, DEBRA, E.;PROGULSKE-FOX, ANN;OSTROV, DAVID, A.
发明人
DUNN, WILLIAM, A.;AKIN, DEBRA, E.;PROGULSKE-FOX, ANN;OSTROV, DAVID, A.