发明名称 |
Inhibitors of biofilm formation of gram-positive and gram-negative bacteria |
摘要 |
<p>The present invention relates to the use of compounds as broad spectrum inhibitors of bacterial biofilm formation. In particular the invention refers to a family of compounds that block the quorum sensing system of Gram-negative and Gram-positive bacteria, a process for their manufacture, pharmaceutical compositions containing them and to their use for the treatment and prevention of bacterial damages and diseases, in particular for diseases where there is an advantage in inhibiting quorum sensing regulated phenotypes of pathogens.</p> |
申请公布号 |
EP2078713(A1) |
申请公布日期 |
2009.07.15 |
申请号 |
EP20070150479 |
申请日期 |
2007.12.28 |
申请人 |
QUONOVA GMBH |
发明人 |
AMMENDOLA, ALDO;WIEBER, TANJA;WUZIK, ANDREAS;LANG, MARTIN |
分类号 |
C07D211/60;A61K31/445;A61P31/04;C07D231/40 |
主分类号 |
C07D211/60 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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